On November 22, 1858, General William Larimer and Captain Jonathan Cox, Esquire, both land speculators from eastern Kansas Territory, placed cottonwood logs to stake a claim on the bluff overlooking the confluence of the South Platte River and Cherry Creek, across the creek from the existing mining settlement of Auraria, and on the site of the existing townsite of St. Charles. Larimer named the townsite Denver City to curry favor with Kansas Territorial Governor James W. Denver. Larimer hoped the town's name would help make it the county seat of Arapaho County but, unbeknownst to him, Governor Denver had already resigned from office. The location was accessible to existing trails and was across the South Platte River from the site of seasonal encampments of the Cheyenne and Arapaho. The site of these first towns is now the site of Confluence Park near downtown Denver. Larimer, along with associates in the St. Charles City Land Company, sold parcels in the town to merchants and miners, with the intention of creating a major city that would cater to new immigrants. Denver City was a frontier town, with an economy based on servicing local miners with gambling, saloons, livestock and goods trading. In the early years, land parcels were often traded for grubstakes or gambled away by miners in Auraria. In May 1859, Denver City residents donated 53 lots to the Leavenworth & Pike's Peak Express in order to secure the region's first overland wagon route. Offering daily service for "passengers, mail, freight, and gold," the Express reached Denver on a trail that trimmed westward travel time from twelve days to six. In 1863, Western Union furthered Denver's dominance of the region by choosing the city for its regional terminus.
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The average amount of time people spend commuting on public transit in Denver and Boulder, Colorado—for example, to and from work, on a weekday—is 77 minutes; 31% of public transit riders ride for more than 2 hours every day. The average amount of time people wait at a stop or station for public transit is 14 minutes, while 25% of riders wait for over 20 minutes, on average, every day. The average distance people usually ride in a single trip with public transit is 6.96 miles (11.20 km), while 31% travel over 7.46 miles (12.01 km) in a single direction.
Denver is ranked as a Beta- world city by the Globalization and World Cities Research Network. With an estimated population of 704,621 in 2017, Denver is the 19th-most populous U.S. city, and with a 17.41% increase since the 2010 United States Census, it has been one of the fastest-growing major cities in the United States. The 10-county Denver-Aurora-Lakewood, CO Metropolitan Statistical Area had an estimated 2017 population of 2,888,227 and is the 19th most populous U.S. metropolitan statistical area. The 12-city Denver-Aurora, CO Combined Statistical Area had an estimated 2017 population of 3,515,374 and is the 15th most populous U.S. metropolitan area. Denver is the most populous city of the 18-county Front Range Urban Corridor, an oblong urban region stretching across two states with an estimated 2017 population of 4,895,589. Denver is the most populous city within a 500-mile (800 km) radius and the second-most populous city in the Mountain West after Phoenix, Arizona. In 2016, Denver was named the best place to live in the United States by U.S. News & World Report.
As of the 2010 census, the population of the City and County of Denver was 600,158, making it the 24th most populous U.S. city. The Denver-Aurora-Lakewood, CO Metropolitan Statistical Area had an estimated 2013 population of 2,697,476 and ranked as the 21st most populous U.S. metropolitan statistical area, and the larger Denver-Aurora-Boulder Combined Statistical Area had an estimated 2013 population of 3,277,309 and ranked as the 16th most populous U.S. metropolitan area. Denver is the most populous city within a radius centered in the city and of 550-mile (890 km) magnitude. Denverites is a term used for residents of Denver.